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Partners Institutional Biosafety Committee (PIBC)


Next PIBC Meeting: April 28th, 2014

Submissions for this meeting must be received by April 9th.


Welcome to the Partners Institutional Biosafety Committee (PIBC). This website includes:

  • Information about the PIBC.
  • Information about the transition from the Harvard Medical School Committee on Microbiological Safety (COMS) to the new PIBC.
  • Information for investigators who are conducting or planning to conduct research with recombinant DNA (rDNA), infectious agents, biological toxins, or human and nonhuman primate materials. 
  • Information about the National Institutes of Health (NIH) Guidelines for Research Involving Recombinant DNA Molecules (NIH Guidelines), the Centers for Disease Control and Prevention (CDC) - NIH Biosafety in Microbiological and Biomedical Laboratories, and relevant federal, state, and local regulations.

Transition from Harvard Medical School Committee on Microbiological Safety (COMS) to PIBC

On November 1, 2011, the review and oversight of Biological Research at Partners Healthcare System (PHS) institutions (i.e., Massachusetts General Hospital, Brigham and Women's Hospital, and McLean Hospital) transitioned from COMS to the new PIBC. COMS will no longer accept submissions from Partners investigators.

For this transition, all registrations reviewed and approved by COMS were migrated to the new Insight Research Portal eIBC Electronic Submission System. Therefore, investigators will not need to re-register current Biological Research.  However, changes to currently approved research, for example, annual updates and amendments, will require use of the eIBC system. Additionally, during the first renewal or amendment of a COMS approved registration we require that the new PIBC forms be completed to ensure that the data in eIBC is the most up to date.  For information regarding using the eIBC portal, refer to the training page of the PIBC website.

For any questions concerning the transition from COMS to the PIBC, please contact the Office of the PIBC.

Sign up for research compliance-related updates from the PIBC